IL-1 beta antibody (AA 170-269)

Catalog No. ABIN516996

This anti-IL-1 beta antibody is a Mouse Monoclonal antibody detecting IL-1 beta in WB, ELISA, IP and IF. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for IL-1 beta antibody (AA 170-269) (ABIN516996)

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-1 beta antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: 2A8

Product Details anti-IL-1 beta Antibody

Binding Specificity: AA 170-269

Purpose: Mouse monoclonal antibody raised against a partial recombinant IL1B.

Sequence: DKIPVALGLK EKNLYLSCVL KDDKPTLQLE SVDPKNYPKK KMEKRFVFNK IEINNKLEFE SAQFPNWYIS TSQAENMPVF LGGTKGGQDI TDFTMQFVSS

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: IL1B (AAH08678, 170 a.a. ~ 269 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-IL-1 beta antibody (ABIN516996)

Mak, Cowan, Popovic, Colterjohn, Singh, Ghert: "Upregulation of MMP-13 via Runx2 in the stromal cell of Giant Cell Tumor of bone." in: Bone, Vol. 45, Issue 2, pp. 377-86, (2009) (PubMed).

Target Details for IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Alternative Name: IL1B

Background: Full Gene Name: interleukin 1, beta
Synonyms: IL-1,IL1-BETA,IL1F2

Gene ID: 3553

Pathways: NF-kappaB Signaling, Interferon-gamma Pathway, TLR Signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome