TLR4 antibody (AA 214-291)

Catalog No. ABIN520975

This Mouse Monoclonal antibody specifically detects TLR4 in IHC (p). It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for TLR4 antibody (AA 214-291) (ABIN520975)

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLR4 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3B6

Product Details anti-TLR4 Antibody

Binding Specificity: AA 214-291

Purpose: Mouse monoclonal antibody raised against a partial recombinant TLR4.

Sequence: PMNFIQPGAF KEIRLHKLTL RNNFDSLNVM KTCIQGLAGL EVHRLVLGEF RNEGNLEKFD KSALEGLCNL TIEEFRLA

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: TLR4 (NP_612564, 214 a.a. ~ 291 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Suggested Applications*:elisa,western blotting,immunohistochemistry (paraffin-embedded sections)
*We do not guarantee this product working for suggested applications.
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-TLR4 antibody (ABIN520975)

Pohjanen, Koivurova, Huhta, Helminen, Mäkinen, Karhukorpi, Joensuu, Koistinen, Valtonen, Niemelä, Karttunen, Karttunen: "Toll-Like Receptor 4 Wild Type Homozygozity of Polymorphisms +896 and +1196 Is Associated with High Gastrin Serum Levels and Peptic Ulcer Risk." in: PLoS ONE, Vol. 10, Issue 7, pp. e0131553, (2015) (PubMed).

Target Details for TLR4

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Alternative Name: TLR4

Background: Full Gene Name: toll-like receptor 4
Synonyms: ARMD10,CD284,TOLL,hToll

Gene ID: 7099

NCBI Accession: NM_138554

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins