SOCS3 antibody (AA 1-225)

Catalog No. ABIN522456

Cited in 1 publication. The Mouse Monoclonal anti-SOCS3 antibody (Clone 1E4) (ABIN522456) specifically detects SOCS3 in ELISA, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for SOCS3 antibody (AA 1-225) (ABIN522456)

Target: SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SOCS3 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1E4

Product Details anti-SOCS3 Antibody

Binding Specificity: AA 1-225

Purpose: Mouse monoclonal antibody raised against a full length recombinant SOCS3.

Sequence: MVTHSKFPAA GMSRPLDTSL RLKTFSSKSE YQLVVNAVRK LQESGFYWSA VTGGEANLLL SAEPAGTFLI RDSSDQRHFF TLSVKTQSGT KNLRIQCEGG SFSLQSDPRS TQPVPRFDCV LKLVHHYMPP PGAPSFPSPP TEPSSEVPEQ PSAQPLPGSP PRRAYYIYSG GEKIPLVLSR PLSSNVATLQ HLCRKTVNGH LDSYEKVTQL PGPIREFLDQ YDAPL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SOCS3 (AAH60858, 1 a.a. ~ 225 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SOCS3 antibody (ABIN522456)

Pierconti, Martini, Pinto, Cenci, Capodimonti, Calarco, Bassi, Larocca: "Epigenetic silencing of SOCS3 identifies a subset of prostate cancer with an aggressive behavior." in: The Prostate, Vol. 71, Issue 3, pp. 318-25, (2011) (PubMed).

Target Details for SOCS3

Target: SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

Alternative Name: SOCS3

Background: Full Gene Name: suppressor of cytokine signaling 3
Synonyms: ATOD4,CIS3,Cish3,MGC71791,SOCS-3,SSI-3,SSI3

Gene ID: 9021

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus, Hepatitis C