MIB2 antibody (AA 381-480)

Catalog No. ABIN530831

There is 1 publication for this product available. The Mouse Monoclonal anti-MIB2 antibody is suitable to detect MIB2 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for MIB2 antibody (AA 381-480) (ABIN530831)

Target: MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MIB2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1B5

Product Details anti-MIB2 Antibody

Binding Specificity: AA 381-480

Purpose: Mouse monoclonal antibody raised against a partial recombinant MIB2.

Sequence: IGDLDTVKRL QAGHGEWTDD MAPALGRVGK VVKVFGDGNL RVAVAGQRWT FSPSCLVAYR PEEDANLDVA ERARENKSSL SVALDKLRAQ KSDPEHPGRL

Cross-Reactivity: Human

Immunogen: MIB2 (AAH37542, 381 a.a. ~ 480 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In ascites fluid

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-MIB2 antibody (ABIN530831)

Jurd, Thornton, Wang, Luong, Phamluong, Kharazia, Gibb, Ron: "Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner." in: The Journal of biological chemistry, Vol. 283, Issue 1, pp. 301-10, (2007) (PubMed).

Target Details for MIB2

Target: MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))

Alternative Name: MIB2

Background: Full Gene Name: mindbomb homolog 2 (Drosophila)
Synonyms: FLJ20648,FLJ39787,ZZANK1,ZZZ5

Gene ID: 142678

Pathways: Notch Signaling