PARK7/DJ1 antibody (AA 1-189)

Catalog No. ABIN532936

Product Details anti-PARK7/DJ1 Antibody

Target: PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

Binding Specificity: AA 1-189

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PARK7/DJ1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against full length recombinant PARK7.

Cross-Reactivity: Human

Immunogen: Recombinant protein corresponding to amino acids 1-189 of human PARK7.

Clone: 1B11

Isotype: IgG1

Application Details

Application Notes: Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS, pH 7.4 (10 % glycerol, 0.02 % sodium azide).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-PARK7/DJ1 antibody (ABIN532936)

Meulener, Graves, Sampathu, Armstrong-Gold, Bonini, Giasson: "DJ-1 is present in a large molecular complex in human brain tissue and interacts with alpha-synuclein." in: Journal of neurochemistry, Vol. 93, Issue 6, pp. 1524-32, (2005) (PubMed).

Junn, Taniguchi, Jeong, Zhao, Ichijo, Mouradian: "Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 27, pp. 9691-6, (2005) (PubMed).

Zhou, Freed: "DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity." in: The Journal of biological chemistry, Vol. 280, Issue 52, pp. 43150-8, (2005) (PubMed).

Target Details for PARK7/DJ1

Target: PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

Alternative Name: DJ-1 / PARK7 (PARK7 Products)

Synonyms: DJ-1 antibody, DJ1 antibody, CAP1 antibody, Dj1 antibody, SP22 antibody, dj1 antibody, zgc:103725 antibody, park7b antibody, park7 antibody, park7a antibody, Parkinsonism associated deglycase antibody, Parkinson disease (autosomal recessive, early onset) 7 antibody, parkinson protein 7 antibody, parkinson protein 7 S homeolog antibody, parkinson protein 7 L homeolog antibody, PARK7 antibody, Park7 antibody, park7 antibody, park7.S antibody, park7.L antibody

Gene ID: 11315

NCBI Accession: NM_007262

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport