INPP5D antibody (N-Term)

Catalog No. ABIN535283

Product Details anti-INPP5D Antibody

Target: INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))

Binding Specificity: N-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This INPP5D antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purpose: Mouse monoclonal antibody raised against synthetic peptide of INPP5D.

Specificity: This antibody reacts with SHIP-1, a phosphoinositide phosphatase largely confined to hematopoietic cells. Multiple forms of SHIP-1 have been reported with molecular weights of 110, 125, 130, 135 and 145 KDa.

Cross-Reactivity: Human

Immunogen: A synthetic peptide corresponding to N-terminus human INPP5D.

Clone: SHIP-01

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry (2-5 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS, pH 7.4 (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.

References for anti-INPP5D antibody (ABIN535283)

Rotblat, Yizhar, Haklai, Ashery, Kloog: "Ras and its signals diffuse through the cell on randomly moving nanoparticles." in: Cancer research, Vol. 66, Issue 4, pp. 1974-81, (2006) (PubMed).

Roy, Plowman, Rotblat, Prior, Muncke, Grainger, Parton, Henis, Kloog, Hancock: "Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling." in: Molecular and cellular biology, Vol. 25, Issue 15, pp. 6722-33, (2005) (PubMed).

Rotblat, Prior, Muncke, Parton, Kloog, Henis, Hancock: "Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane." in: Molecular and cellular biology, Vol. 24, Issue 15, pp. 6799-810, (2004) (PubMed).

Target Details for INPP5D

Target: INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))

Alternative Name: INPP5D (INPP5D Products)

Synonyms: INPP5D antibody, 256.t00004 antibody, 13.t00027 antibody, ship antibody, ship1 antibody, AI323613 antibody, SHIP antibody, SHIP-1 antibody, SHIP1 antibody, s-SHIP antibody, SIP-145 antibody, hp51CN antibody, inositol polyphosphate-5-phosphatase D antibody, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 antibody, inositol polyphosphate 5-phosphatase antibody, inositol polyphosphate-5-phosphatase D L homeolog antibody, INPP5D antibody, LOC100446045 antibody, inpp5d antibody, EHI_159880 antibody, EHI_153490 antibody, inpp5d.L antibody, LOC100380693 antibody, Inpp5d antibody

Gene ID: 3635

Pathways: TCR Signaling, BCR Signaling, Warburg Effect