HLA-DR1 antibody (PE)
(2 references)-
- Target See all HLA-DR1 products
- HLA-DR1 (MHC Class II HLA-DR1 (HLA-DR1))
- Reactivity
- E. coli
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This HLA-DR1 antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Purpose
- Mouse monoclonal antibody raised against HLA-DR1.
- Specificity
- This antibody specifically binds to the empty but not peptide-loaded form of HLA-DR1. DR is the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).
- Cross-Reactivity
- Human
- Immunogen
- Purified, insoluble DR1 beta chain (DRB1*0101) expressed in Escherichia coli inclusion bodies.
- Clone
- MEM-267
- Isotype
- IgG2b
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anti-MHC Class II HLA-DR1 (HLA-DR1) antibody
HLA-DR1 Reactivity: Human FACS, ELISA, WB Host: Mouse Monoclonal MEM-267 unconjugated
anti-MHC Class II HLA-DR1 (HLA-DR1) antibody (PE)HLA-DR1 Reactivity: Human FACS Host: Mouse Monoclonal MEM-267 PE
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- Application Notes
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Flow Cytometry (5 μg/mL)
The optimal working dilution should be determined by the end user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1 mg/mL
- Buffer
- In PBS (0.2 % BSA, 0.09 % sodium azide)
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
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Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
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-
: "Conformational variation of surface class II MHC proteins during myeloid dendritic cell differentiation accompanies structural changes in lysosomal MIIC." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 8, pp. 4935-47, (2005) (PubMed).
: "Monoclonal antibodies specific for the empty conformation of HLA-DR1 reveal aspects of the conformational change associated with peptide binding." in: The Journal of biological chemistry, Vol. 279, Issue 16, pp. 16561-70, (2004) (PubMed).
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: "Conformational variation of surface class II MHC proteins during myeloid dendritic cell differentiation accompanies structural changes in lysosomal MIIC." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 8, pp. 4935-47, (2005) (PubMed).
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- Target
- HLA-DR1 (MHC Class II HLA-DR1 (HLA-DR1))
- Alternative Name
- HLA-DR1 (HLA-DR1 Products)
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