SH3BP2 antibody (pSer427)

Catalog No. ABIN538209

Product Details anti-SH3BP2 Antibody

Target: SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

Binding Specificity: pSer427

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3BP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Purpose: Rabbit polyclonal antibody raised against synthetic phosphopeptide of SH3BP2.

Specificity: This antibody is specific to phosphorylated human SH3BP2 protein at the pS427 residue. Minimal reactivity is expected with the non-phosphorylated form of the protein.

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S427 of human SH3BP2.

Application Details

Application Notes: ELISA (1:2000-1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-SH3BP2 antibody (ABIN538209)

Foucault, Liu, Bernard, Deckert: "The chaperone protein 14-3-3 interacts with 3BP2/SH3BP2 and regulates its adapter function." in: The Journal of biological chemistry, Vol. 278, Issue 9, pp. 7146-53, (2003) (PubMed).

Lo, Faiyaz-Ul-Haque, Kennedy, Aviv, Tsui, Teebi: "Novel mutation in the gene encoding c-Abl-binding protein SH3BP2 causes cherubism." in: American journal of medical genetics. Part A, Vol. 121A, Issue 1, pp. 37-40, (2003) (PubMed).

Imai, Kanno, Moriya, Kayano, Seino, Matsubara, Yamada: "A missense mutation in the SH3BP2 gene on chromosome 4p16.3 found in a case of nonfamilial cherubism." in: The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, Vol. 40, Issue 6, pp. 632-8, (2003) (PubMed).

Target Details for SH3BP2

Target: SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

Alternative Name: SH3BP2 (SH3BP2 Products)

Synonyms: SH3BP2 antibody, 3BP-2 antibody, 3BP2 antibody, CRBM antibody, CRPM antibody, SH3 domain binding protein 2 antibody, SH3-domain binding protein 2 antibody, SH3BP2 antibody, Sh3bp2 antibody

Gene ID: 6452

Pathways: TCR Signaling