FOXP3 antibody

Catalog No. ABIN540719

Product Details anti-FOXP3 Antibody

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of FOXP3.

Specificity: This antibody is specific to human FOXP3.

Cross-Reactivity: Human, Mouse

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to smino acids 400-431 of human FOXP3.

Application Details

Application Notes: Western Blot (1:1000-1:5000)
Immunohistochemistry (Frozen sections) (1:50)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In Tris-citrate/phosphate buffer, pH 7.0-8.0

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

References for anti-FOXP3 antibody (ABIN540719)

Ostroukhova, Qi, Oriss, Dixon-McCarthy, Ray, Ray: "Treg-mediated immunosuppression involves activation of the Notch-HES1 axis by membrane-bound TGF-beta." in: The Journal of clinical investigation, Vol. 116, Issue 4, pp. 996-1004, (2006) (PubMed).

Ochando, Yopp, Yang, Garin, Li, Boros, Llodra, Ding, Lira, Krieger, Bromberg: "Lymph node occupancy is required for the peripheral development of alloantigen-specific Foxp3+ regulatory T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 6993-7005, (2005) (PubMed).

Polanczyk, Carson, Subramanian, Afentoulis, Vandenbark, Ziegler, Offner: "Cutting edge: estrogen drives expansion of the CD4+CD25+ regulatory T cell compartment." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 4, pp. 2227-30, (2004) (PubMed).

Target Details for FOXP3

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Alternative Name: FOXP3 (FOXP3 Products)

Synonyms: foxp3 antibody, FOXP3 antibody, AIID antibody, DIETER antibody, IPEX antibody, PIDX antibody, XPID antibody, JM2 antibody, scurfin antibody, sf antibody, RGD1562112 antibody, forkhead box P3 antibody, forkhead box P3a antibody, forkhead box P3 L homeolog antibody, FOXP3 antibody, foxp3a antibody, foxp3 antibody, foxp3.L antibody, Foxp3 antibody

Gene ID: 50943

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation