LASS5 antibody (N-Term)

Catalog No. ABIN541788

Product Details anti-LASS5 Antibody

Target: LASS5 (LAG1 Homolog, Ceramide Synthase 5 (LASS5))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LASS5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of LASS5.

Cross-Reactivity: Human, Mouse, Rat

Immunogen: A synthetic peptide corresponding to N-terminus 18 amino acids of human LASS5.

Application Details

Application Notes: Western Blot (1-2 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.02 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-LASS5 antibody (ABIN541788)

Separovic, Breen, Joseph, Bielawski, Pierce, VAN Buren, Gudz: "Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells." in: Anticancer research, Vol. 32, Issue 3, pp. 753-60, (2012) (PubMed).

Separovic, Breen, Joseph, Bielawski, Pierce, VAN Buren, Gudz: "siRNA-mediated down-regulation of ceramide synthase 1 leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy." in: Anticancer research, Vol. 32, Issue 7, pp. 2479-85, (2012) (PubMed).

Spassieva, Seo, Jiang, Bielawski, Alvarez-Vasquez, Jazwinski, Hannun, Obeid: "Necessary role for the Lag1p motif in (dihydro)ceramide synthase activity." in: The Journal of biological chemistry, Vol. 281, Issue 45, pp. 33931-8, (2006) (PubMed).

Lahiri, Futerman: "LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donor." in: The Journal of biological chemistry, Vol. 280, Issue 40, pp. 33735-8, (2005) (PubMed).

Riebeling, Allegood, Wang, Merrill, Futerman: "Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors." in: The Journal of biological chemistry, Vol. 278, Issue 44, pp. 43452-9, (2003) (PubMed).

Target Details for LASS5

Target: LASS5 (LAG1 Homolog, Ceramide Synthase 5 (LASS5))

Alternative Name: LASS5 (LASS5 Products)

Synonyms: lass5 antibody, trh4 antibody, LASS5 antibody, Trh4 antibody, 2310081H14Rik antibody, AU045339 antibody, AW544927 antibody, Lass5 antibody, ceramide synthase 5 antibody, ceramide synthase 5 S homeolog antibody, CERS5 antibody, cers5 antibody, cers5.S antibody, Cers5 antibody

Gene ID: 91012