Dnmt2 antibody (AA 353-383)

Catalog No. ABIN543148

Product Details anti-Dnmt2 Antibody

Target: Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

Binding Specificity: AA 353-383

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dnmt2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of TRDMT1.

Cross-Reactivity: Human, Mouse

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 353-383 at C-terminus of human TRDMT1.

Application Details

Application Notes: Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-Dnmt2 antibody (ABIN543148)

Hermann, Schmitt, Jeltsch: "The human Dnmt2 has residual DNA-(cytosine-C5) methyltransferase activity." in: The Journal of biological chemistry, Vol. 278, Issue 34, pp. 31717-21, (2003) (PubMed).

Dong, Yoder, Zhang, Zhou, Bestor, Cheng: "Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA." in: Nucleic acids research, Vol. 29, Issue 2, pp. 439-48, (2001) (PubMed).

Franchina, Hooper, Kay: "Five novel alternatively spliced transcripts of DNA (cytosine-5) methyltransferase 2 in human peripheral blood leukocytes." in: The international journal of biochemistry & cell biology, Vol. 33, Issue 11, pp. 1104-15, (2001) (PubMed).

Target Details for Dnmt2

Target: Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

Alternative Name: DNMT2 / TRDMT1 (TRDMT1 Products)

Synonyms: MGC89267 antibody, DMNT2 antibody, DNMT2 antibody, MHSAIIP antibody, PUMET antibody, RNMT1 antibody, Dnmt2 antibody, Rnmt2 antibody, dnmt2 antibody, tRNA aspartic acid methyltransferase 1 antibody, tRNA aspartic acid methyltransferase 1 L homeolog antibody, trdmt1 antibody, TRDMT1 antibody, Trdmt1 antibody, trdmt1.L antibody

Gene ID: 1787