DNMT3B
Reactivity: Human, Mouse, Rat
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In PBS (0.09 % sodium azide)
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Koturbash, Boyko, Rodriguez-Juarez, McDonald, Tryndyak, Kovalchuk, Pogribny, Kovalchuk: "Role of epigenetic effectors in maintenance of the long-term persistent bystander effect in spleen in vivo." in: Carcinogenesis, Vol. 28, Issue 8, pp. 1831-8, (2007) (PubMed).
Fabbri, Garzon, Cimmino, Liu, Zanesi, Callegari, Liu, Alder, Costinean, Fernandez-Cymering, Volinia, Guler, Morrison, Chan, Marcucci, Calin, Huebner, Croce: "MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 40, pp. 15805-10, (2007) (PubMed).
Tryndyak, Muskhelishvili, Kovalchuk, Rodriguez-Juarez, Montgomery, Churchwell, Ross, Beland, Pogribny: "Effect of long-term tamoxifen exposure on genotoxic and epigenetic changes in rat liver: implications for tamoxifen-induced hepatocarcinogenesis." in: Carcinogenesis, Vol. 27, Issue 8, pp. 1713-20, (2006) (PubMed).