Cullin 4A antibody (N-Term)

Catalog No. ABIN543950

Product Details anti-Cullin 4A Antibody

Target: Cullin 4A (CUL4A)

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 4A antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of CUL4A.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human CUL4A.

Application Details

Application Notes: Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-Cullin 4A antibody (ABIN543950)

Huang, Chen: "VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation." in: Oncogene, Vol. 27, Issue 29, pp. 4056-64, (2008) (PubMed).

Hu, Zacharek, He, Lee, Shumway, Duronio, Xiong: "WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase." in: Genes & development, Vol. 22, Issue 7, pp. 866-71, (2008) (PubMed).

Wen, Duus, Friedrich, de Noronha: "The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor." in: The Journal of biological chemistry, Vol. 282, Issue 37, pp. 27046-57, (2007) (PubMed).

Target Details for Cullin 4A

Target: Cullin 4A (CUL4A)

Alternative Name: Cullin-4A (CUL4A Products)

Synonyms: zgc:64071 antibody, CUL4A antibody, 2810470J21Rik antibody, AW495282 antibody, RGD1563853 antibody, cullin 4A antibody, CUL4A antibody, cul4a antibody, Cul4a antibody

Gene ID: 8451