CDC6 antibody (N-Term)

Catalog No. ABIN545777

Product Details anti-CDC6 Antibody

Target: CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of CDC6.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human CDC6.

Application Details

Application Notes: ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-CDC6 antibody (ABIN545777)

Alexandrow, Hamlin: "Cdc6 chromatin affinity is unaffected by serine-54 phosphorylation, S-phase progression, and overexpression of cyclin A." in: Molecular and cellular biology, Vol. 24, Issue 4, pp. 1614-27, (2004) (PubMed).

Clay-Farrace, Pelizon, Santamaria, Pines, Laskey: "Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1." in: The EMBO journal, Vol. 22, Issue 3, pp. 704-12, (2003) (PubMed).

Yim, Jin, Park, Choi, Lee: "Caspase-3-mediated cleavage of Cdc6 induces nuclear localization of p49-truncated Cdc6 and apoptosis." in: Molecular biology of the cell, Vol. 14, Issue 10, pp. 4250-9, (2003) (PubMed).

Target Details for CDC6

Target: CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))

Alternative Name: CDC6 (CDC6 Products)

Synonyms: CDC18L antibody, HsCDC18 antibody, HsCDC6 antibody, cell division cycle 6 antibody, CDC6 antibody, Cdc6 antibody

Gene ID: 990

Pathways: DNA Replication, Synthesis of DNA