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PDE10A antibody (N-Term)
PDE10A
Reactivity: Human, Rat, Dog, Horse, Rabbit
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PDE10A Antibody
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Target
See all PDE10A Antibodies
PDE10A
(phosphodiesterase 10A (PDE10A))
Binding Specificity
All epitopes for PDE10A antibodies
N-Term
Reactivity
Human, Rat, Dog, Horse, Rabbit
Host
All hosts for PDE10A antibodies
Rabbit
Clonality
All clonalities for PDE10A antibodies
Polyclonal
Conjugate
All conjugates for PDE10A antibodies
This PDE10A antibody is un-conjugated
Application
All applications for PDE10A antibodies
Western Blotting (WB)
Sequence
SLHPQVLDEF VSESVSAETV EKWLKRKNNK SEDESAPKEV SRYQDTNMQG
Predicted Reactivity
Dog: 93%, Horse: 93%, Human: 100%, Rabbit: 86%, Rat: 86%
Characteristics
This is a rabbit polyclonal antibody against PDE10A. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human PDE10A
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for PDE10A
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Target
PDE10A
(phosphodiesterase 10A (PDE10A))
Alternative Name
PDE10A (PDE10A Products )
Synonyms
HSPDE10A antibody, Pde10a3 antibody, phosphodiesterase 10A antibody, PDE10A antibody, Pde10a antibody
Background
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. Alias Symbols: PDE10A, Protein Interaction Partner: TOP1, UBC, WDR3, CASP3, Protein Size: 779
Gene ID
10846
UniProt
Q9Y233
Pathways
cAMP Metabolic Process
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