Serotonin Receptor 6 antibody (C-Term)

Catalog No. ABIN5514475

The Rabbit Polyclonal anti-Serotonin Receptor 6 antibody is suitable to detect Serotonin Receptor 6 in samples from Human. It has been validated for WB.

Quick Overview for Serotonin Receptor 6 antibody (C-Term) (ABIN5514475)

Target: Serotonin Receptor 6 (HTR6)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Serotonin Receptor 6 Antibody

Binding Specificity: C-Term

Purpose: HTR6 Antibody - C-terminal region

Sequence: PDSDSDSDAG SGGSSGLRLT AQLLLPGEAT QDPPLPTRAA AAVNFFNIDP

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HTR6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP81823-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Serotonin Receptor 6

Target: Serotonin Receptor 6 (HTR6)

Alternative Name: HTR6

Background:

Background Information: This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor.

Gene Name: 5-hydroxytryptamine receptor 6

Alternative Symbols: 5-HT6, 5-HT6R

Protein Name: 5-hydroxytryptamine receptor 6

Molecular Weight: 48 kDa

Gene ID: 3362

NCBI Accession: NP_000862

UniProt: P50406

Pathways: JAK-STAT Signaling