AFF4 antibody (Middle Region)

Catalog No. ABIN5514480

Product Details anti-AFF4 Antibody

Target: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AFF4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SSGTNSSGQR HDRESYNNSG SSSRKKGQHG SEHSKSRSSS PGKPQAVSSL

Characteristics: This is a rabbit polyclonal antibody against AFF4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human AFF4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AFF4

Target: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Alternative Name: AFF4 (AFF4 Products)

Synonyms: AFF4 antibody, RA_m002_jsmFBA6Br antibody, AF5Q31 antibody, MCEF antibody, Alf4 antibody, Laf4l antibody, AF4/FMR2 family member 4 L homeolog antibody, AF4/FMR2 family member 4 antibody, AF4/FMR2 family, member 4 antibody, aff4.L antibody, AFF4 antibody, aff4 antibody, Aff4 antibody

Background: The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins.

Alias Symbols: AFF4, AF5Q31, MCEF, HSPC092,

Protein Interaction Partner: UBC, TRAF2, SIAH1, GOLGA2, AP2B1, MTUS2, HECW2, CDK15, CDK9, MLLT1, MED19, EAF1, EAF2, tat, AFF4, ELL2, MED26, ELL, MLLT3, AFF1, CCNT2, CCNT1, GRK5, KMT2A, SPP1,

Protein Size: 353

Gene ID: 27125