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Complement Factor B antibody (N-Term)
CFB
Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Sheep, Dog
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Complement Factor B Antibody
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Target
See all Complement Factor B (CFB) Antibodies
Complement Factor B (CFB)
Binding Specificity
All epitopes for Complement Factor B antibodies
N-Term
Reactivity
Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Sheep, Dog
Host
All hosts for Complement Factor B antibodies
Rabbit
Clonality
All clonalities for Complement Factor B antibodies
Polyclonal
Conjugate
All conjugates for Complement Factor B antibodies
This Complement Factor B antibody is un-conjugated
Application
All applications for Complement Factor B antibodies
Western Blotting (WB)
Sequence
NGAGYCSNPG IPIGTRKVGS QYRLEDSVTY HCSRGLTLRG SQRRTCQEGG
Predicted Reactivity
Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 93%
Characteristics
This is a rabbit polyclonal antibody against CFAB. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human CFAB
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for Complement Factor B
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Target
Complement Factor B (CFB)
Alternative Name
CFAB (CFB Products )
Synonyms
AHUS4 antibody, BF antibody, BFD antibody, CFAB antibody, FB antibody, FBI12 antibody, GBG antibody, H2-Bf antibody, PBF2 antibody, bf antibody, Bf-1 antibody, Brre-Bf antibody, zgc:114032 antibody, Bf antibody, Sp152 antibody, bfb-A antibody, Bf B antibody, LOC397725 antibody, bf/c2 antibody, CFB antibody, AI195813 antibody, AI255840 antibody, B antibody, C2 antibody, Fb antibody, Da1-24 antibody, complement factor B antibody, complement factor B S homeolog antibody, complement factor B L homeolog antibody, CFB antibody, cfb antibody, bf antibody, cfb.S antibody, cfb.L antibody, bf/c2 antibody, LOC100555981 antibody, Cfb antibody
Background
CFAB is a factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B- lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. Alias Symbols: CFB, BF, BFD, Protein Interaction Partner: FN1, LAMC3, RPA2, ALB, CFP, C3, Protein Size: 764
Gene ID
629
NCBI Accession
NP_001701
UniProt
P00751
Pathways
Complement System , Proton Transport , Ribonucleoside Biosynthetic Process
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