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MDFI antibody (Middle Region)

MDFI Reactivity: Human, Cow, Dog, Pig, Rabbit, Sheep WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5514974
  • Target See all MDFI Antibodies
    MDFI (MyoD Family Inhibitor (MDFI))
    Binding Specificity
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Cow, Dog, Pig, Rabbit, Sheep
    Host
    • 30
    • 2
    • 2
    Rabbit
    Clonality
    • 33
    • 1
    Polyclonal
    Conjugate
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MDFI antibody is un-conjugated
    Application
    • 13
    • 13
    • 12
    • 10
    • 3
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Sequence
    AVTCQPQGNP LGCTPLLPND SGHPSELGGT RRAGNGALGG PKAHRKLQTH
    Predicted Reactivity
    Cow: 79%, Dog: 79%, Human: 100%, Pig: 86%, Rabbit: 79%, Sheep: 86%
    Characteristics
    This is a rabbit polyclonal antibody against MDFI. It was validated on Western Blot.
    Purification
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of Human MDFI
    Top Product
    Discover our top product MDFI Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MDFI (MyoD Family Inhibitor (MDFI))
    Alternative Name
    MDFI (MDFI Products)
    Synonyms
    MDFI antibody, I-MF antibody, I-mfa antibody, I-mf antibody, RGD1560271 antibody, MyoD family inhibitor antibody, MDFI antibody, Mdfi antibody
    Background
    This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.

    Alias Symbols: MDFI,

    Protein Interaction Partner: PDIA5, USP20, ARID5A, ZNF266, KAT5, SPRY2, SPRY1, NR1H3, ZBTB24, ARHGAP32, KIAA0040, CREB5, MAGED1, ZNF264, GTF3C5, APLN, AKAP17A, ZNF230, ZNF223, ZNF155, ZNF138, ZNF136, ZNF124, ZNF79, WNT11, VHL, NR1H2, TYRO3, TNP2, TNNI1, TGIF1, GNAI2, GATA2, EIF4A2, D

    Protein Size: 246
    Gene ID
    4188
    NCBI Accession
    NP_005577
    UniProt
    Q99750
    Pathways
    Maintenance of Protein Location
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