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MDFI antibody (Middle Region)
MDFI
Reactivity: Human, Cow, Dog, Pig, Rabbit, Sheep
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MDFI Antibody
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Target
See all MDFI Antibodies
MDFI
(MyoD Family Inhibitor (MDFI))
Binding Specificity
All epitopes for MDFI antibodies
Middle Region
Reactivity
Human, Cow, Dog, Pig, Rabbit, Sheep
Host
All hosts for MDFI antibodies
Rabbit
Clonality
All clonalities for MDFI antibodies
Polyclonal
Conjugate
All conjugates for MDFI antibodies
This MDFI antibody is un-conjugated
Application
All applications for MDFI antibodies
Western Blotting (WB)
Sequence
AVTCQPQGNP LGCTPLLPND SGHPSELGGT RRAGNGALGG PKAHRKLQTH
Predicted Reactivity
Cow: 79%, Dog: 79%, Human: 100%, Pig: 86%, Rabbit: 79%, Sheep: 86%
Characteristics
This is a rabbit polyclonal antibody against MDFI. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human MDFI
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for MDFI
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Target
MDFI
(MyoD Family Inhibitor (MDFI))
Alternative Name
MDFI (MDFI Products )
Synonyms
MDFI antibody, I-MF antibody, I-mfa antibody, I-mf antibody, RGD1560271 antibody, MyoD family inhibitor antibody, MDFI antibody, Mdfi antibody
Background
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. Alias Symbols: MDFI, Protein Interaction Partner: PDIA5, USP20, ARID5A, ZNF266, KAT5, SPRY2, SPRY1, NR1H3, ZBTB24, ARHGAP32, KIAA0040, CREB5, MAGED1, ZNF264, GTF3C5, APLN, AKAP17A, ZNF230, ZNF223, ZNF155, ZNF138, ZNF136, ZNF124, ZNF79, WNT11, VHL, NR1H2, TYRO3, TNP2, TNNI1, TGIF1, GNAI2, GATA2, EIF4A2, D Protein Size: 246
Gene ID
4188
NCBI Accession
NP_005577
UniProt
Q99750
Pathways
Maintenance of Protein Location
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