SOCS4 antibody (N-Term)

Catalog No. ABIN5515155

This Rabbit Polyclonal antibody specifically detects SOCS4 in WB. It exhibits reactivity toward Human.

Quick Overview for SOCS4 antibody (N-Term) (ABIN5515155)

Target: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOCS4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SOCS4 Antibody

Binding Specificity: N-Term

Purpose: SOCS4 Antibody - N-terminal region

Sequence: DVRPKTSRSR SADRKDGYVW SGKKLSWSKK SESYSDAETV NGIEKTEVSL

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SOCS4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP78402-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SOCS4

Target: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Alternative Name: SOCS4

Background:

Background Information: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene Name: suppressor of cytokine signaling 4

Alternative Symbols: SOCS7

Protein Name: suppressor of cytokine signaling 4

Molecular Weight: 51 kDa

Gene ID: 122809

NCBI Accession: NP_543143

UniProt: Q8WXH5

Pathways: JAK-STAT Signaling, EGFR Signaling Pathway