IL2RG antibody (C-Term)

Catalog No. ABIN5515505

The Rabbit Polyclonal anti-IL2RG antibody (ABIN5515505) specifically detects IL2RG in WB. The antibody is reactive with Human samples.

Quick Overview for IL2RG antibody (C-Term) (ABIN5515505)

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL2RG antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IL2RG Antibody

Binding Specificity: C-Term

Purpose: IL2RG Antibody - C-terminal region

Sequence: FSAWSGVSKG LAESLQPDYS ERLCLVSEIP PKGGALGEGP GASPCNQHSP

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human IL2RG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP80633-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL2RG

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Alternative Name: IL2RG

Background:

Background Information: The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.

Gene Name: interleukin 2 receptor subunit gamma

Alternative Symbols: P64, CIDX, IMD4, CD132, SCIDX, IL-2RG, SCIDX1

Protein Name: cytokine receptor common subunit gamma

Molecular Weight: 40 kDa

Gene ID: 3561

NCBI Accession: NP_000197

UniProt: P31785

Pathways: JAK-STAT Signaling, Growth Factor Binding