NCF2 antibody (Middle Region)

Catalog No. ABIN5515573

Product Details anti-NCF2 Antibody

Target: NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCF2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YLEPVELRIH PQQQPQEESS PQSDIPAPPS SKAPGRPQLS PGQKQKEEPK

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NCF2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NCF2

Target: NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))

Alternative Name: NCF2 (NCF2 Products)

Synonyms: MGC81877 antibody, zgc:158405 antibody, noxa2 antibody, p67-phox antibody, p67phox antibody, NCF-2 antibody, NOXA2 antibody, P67-PHOX antibody, P67PHOX antibody, Ncf-2 antibody, neutrophil cytosolic factor 2 antibody, neutrophil cytosolic factor 2 L homeolog antibody, neutrophil cytosol factor 2 antibody, hypothetical protein antibody, NCF2 antibody, ncf2.L antibody, ncf2 antibody, p67phox antibody, VDBG_06643 antibody, PGTG_05816 antibody, LOC100136240 antibody, Ncf2 antibody

Background: This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alias Symbols: NCF-2, NOXA2, P67PHOX, P67-PHOX

Protein Size: 526

Gene ID: 4688

NCBI Accession: NM_000433, NP_000424

UniProt: P19878