SPG7 antibody (N-Term)

Catalog No. ABIN5515659

This Rabbit Polyclonal antibody specifically detects SPG7 in WB. It exhibits reactivity toward Human.

Quick Overview for SPG7 antibody (N-Term) (ABIN5515659)

Target: SPG7 (Spastic Paraplegia 7 (SPG7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPG7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SPG7 Antibody

Binding Specificity: N-Term

Sequence: LWQLLGGTFY FNTSRLKQKN KEKDKSKGKA PEEDEEERRR RERDDQMYRE

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SPG7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPG7

Target: SPG7 (Spastic Paraplegia 7 (SPG7))

Alternative Name: SPG7

Background: This gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.

Alias Symbols: CAR, PGN, CMAR, SPG5C

Protein Size: 489

Gene ID: 6687

NCBI Accession: NM_003119, NP_003110