CD226 antibody (C-Term)

Catalog No. ABIN5515800

This Rabbit Polyclonal antibody specifically detects CD226 in WB. It exhibits reactivity toward Human, Rat and Dog.

Quick Overview for CD226 antibody (C-Term) (ABIN5515800)

Target: CD226

Reactivity: Human, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD226 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD226 Antibody

Binding Specificity: C-Term

Sequence: QASAGENETF VMRLTVAEGK TDNQYTLFVA GGTVLLLLFV ISITTIIVIF

Predicted Reactivity: Dog: 85%, Human: 100%, Rat: 77%

Characteristics: This is a rabbit polyclonal antibody against CD226. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CD226

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD226

Target: CD226

Alternative Name: CD226

Background: This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation.

Alias Symbols: DNAM-1, DNAM1, PTA1, TLiSA1

Protein Interaction Partner: UBC, PVRL2, ITGB2, PVR, FYN,

Protein Size: 336

Gene ID: 10666

NCBI Accession: NM_006566, NP_006557

UniProt: Q15762

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints