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COPS8 antibody (N-Term)
COPS8
Reactivity: Human, Rat, Mouse, Horse, Rabbit, Cow, Guinea Pig, Dog, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-COPS8 Antibody
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Target
See all COPS8 Antibodies
COPS8
(COP9 Signalosome Subunit 8 (COPS8))
Binding Specificity
All epitopes for COPS8 antibodies
N-Term
Reactivity
All reactivities for COPS8 antibodies
Human, Rat, Mouse, Horse, Rabbit, Cow, Guinea Pig, Dog, Zebrafish (Danio rerio)
Host
All hosts for COPS8 antibodies
Rabbit
Clonality
All clonalities for COPS8 antibodies
Polyclonal
Conjugate
All conjugates for COPS8 antibodies
This COPS8 antibody is un-conjugated
Application
All applications for COPS8 antibodies
Western Blotting (WB)
Sequence
QCENQELEAP GGIATPPVYG QLLALYLLHN DMNNARYLWK RIPPAIKSAN
Predicted Reactivity
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
Characteristics
This is a rabbit polyclonal antibody against CSN8. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen for Anti-COPS8 antibody is: synthetic peptide directed towards the N-terminal region of Human CSN8
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for COPS8
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Target
COPS8
(COP9 Signalosome Subunit 8 (COPS8))
Alternative Name
COPS8 (COPS8 Products )
Synonyms
COP9 antibody, CSN8 antibody, SGN8 antibody, csn8 antibody, cops8 antibody, MGC76051 antibody, MGC80215 antibody, DDBDRAFT_0167123 antibody, DDBDRAFT_0233107 antibody, DDB_0167123 antibody, DDB_0233107 antibody, zgc:56319 antibody, zgc:86840 antibody, MGC86182 antibody, 9430009J09Rik antibody, AA408242 antibody, Csn8 antibody, Sgn8 antibody, CONSTITUTIVE PHOTOMORPHOGENIC 9 antibody, COP9 SIGNALOSOME SUBUNIT 8 antibody, DL3095C antibody, EMB143 antibody, EMBRYO DEFECTIVE 143 antibody, FCAALL.131 antibody, FUS7 antibody, FUSCA 7 antibody, FUSCA PROTEIN FUS7 antibody, CG13383 antibody, CG33297 antibody, CG42522 antibody, CH8 antibody, Dch8 antibody, Dmel\\CG42522 antibody, Dmel_CG13383 antibody, l(2)SH1829 antibody, l(2)SH2 1829 antibody, COP9 signalosome subunit 8 antibody, COP9 signalosome subunit 8 S homeolog antibody, COP9 signalosome complex subunit 8 antibody, COP9 signalosome subunit 8 L homeolog antibody, COP9 signalosome, subunit CSN8 antibody, COPS8 antibody, Cops8 antibody, cops8 antibody, cops8.S antibody, CSN8 antibody, csn8 antibody, cops8.L antibody, COP9 antibody
Background
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Alias Symbols: COP9, CSN8, SGN8 Protein Interaction Partner: USHBP1, GPS1, cul1, WDR77, SRRT, COPS7A, VIM, COPS4, FBXO6, FBXW4, COPS5, vpr, IRF5, DDIT3, COPS2, COPS3, COPS6, PINK1, RFWD2, CUL4A, UBC, LRR1, DDA1, DDB2, DCUN1D1, VPRBP, CUL2, CUL3, CUL4B, CUL5, NEDD8, JUN, GFER, ERCC8, DDB1, CTNNB1, RAE1, COPS8, EIF3E Protein Size: 209
Gene ID
10920
UniProt
Q99627
Pathways
Cell Division Cycle
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