RDH5 antibody (Middle Region)

Catalog No. ABIN5516226

Product Details anti-RDH5 Antibody

Target: RDH5 (Retinol Dehydrogenase 5 (11-Cis/9-Cis) (RDH5))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RDH5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RGFRVLASCL TPSGAEDLQR VASSRLHTTL LDITDPQSVQ QAAKWVEMHV

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle terminal region of human RDH5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RDH5

Target: RDH5 (Retinol Dehydrogenase 5 (11-Cis/9-Cis) (RDH5))

Alternative Name: RDH5 (RDH5 Products)

Synonyms: 9cRDH antibody, HSD17B9 antibody, RDH1 antibody, SDR9C5 antibody, RDHB antibody, MGC84134 antibody, RDH5 antibody, rdh1 antibody, hsd17b9 antibody, im:6901729 antibody, si:dkey-102c8.5 antibody, 9-cis antibody, AI987873 antibody, RDH4 antibody, cRDH antibody, retinol dehydrogenase 5 antibody, retinol dehydrogenase 1 antibody, retinol dehydrogenase 5 L homeolog antibody, retinol dehydrogenase 5 (11-cis/9-cis) antibody, RDH5 antibody, rdh1 antibody, rdh5.L antibody, rdh5 antibody, Rdh5 antibody

Background: This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene.

Alias Symbols: RDH1, 9cRDH, SDR9C5, HSD17B9

Protein Size: 318

Gene ID: 5959

NCBI Accession: NM_001199771, NP_001186700

UniProt: Q92781