C1QC antibody (Middle Region)

Catalog No. ABIN5516555

Product Details anti-C1QC Antibody

Target: C1QC (Complement Component 1, Q Subcomponent, C Chain (C1QC))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Pig, Rabbit, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QC antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GKNGPMGPPG MPGVPGPMGI PGEPGEEGRY KQKFQSVFTV TRQTHQPPAP

Predicted Reactivity: Cow: 92%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against C1QC. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human C1QC

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for C1QC

Target: C1QC (Complement Component 1, Q Subcomponent, C Chain (C1QC))

Alternative Name: C1QC (C1QC Products)

Synonyms: c1qc antibody, AI385742 antibody, C1qg antibody, Ciqc antibody, C1Q-C antibody, C1QG antibody, complement C1q C chain antibody, complement component 1, q subcomponent, C chain antibody, C1QC antibody, c1qc antibody, C1qc antibody

Background: This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.

Alias Symbols: C1QG

Protein Interaction Partner: FN1, APOA1, PTX3, FKBP2, C1QB, C1QA,

Protein Size: 245

Gene ID: 714

NCBI Accession: NP_758957

UniProt: P02747

Pathways: Complement System