CASC4 antibody (N-Term)

Catalog No. ABIN5516652

This Rabbit Polyclonal antibody specifically detects CASC4 in WB. It exhibits reactivity toward Human, Mouse, Rabbit, Rat, Cow, Dog and Pig.

Quick Overview for CASC4 antibody (N-Term) (ABIN5516652)

Target: CASC4 (Cancer Susceptibility Candidate 4 (CASC4))

Reactivity: Human, Mouse, Rabbit, Rat, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CASC4 Antibody

Binding Specificity: N-Term

Purpose: CASC4 Antibody - N-terminal region

Sequence: DLLLLVDTHK KQIDQKEADY GRLSSRLQAR EGLGKRCEDD KVKLQNNISY

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CASC4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CASC4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP69163-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CASC4

Target: CASC4 (Cancer Susceptibility Candidate 4 (CASC4))

Alternative Name: CASC4

Background:

Background Information: The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30 % of human breast and 20 % of human ovarian cancers. Alternatively spliced variants encoding different isoforms have been identified for this gene.

Alternative Symbols: H63, CASC4

Protein Name: Protein CASC4

Molecular Weight: 47kDa

Gene ID: 113201

UniProt: Q6P4E1