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DUX4 antibody (Middle Region)
DUX4
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DUX4 Antibody
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Target
See all DUX4 Antibodies
DUX4
(Double Homeobox 4 (DUX4))
Binding Specificity
All epitopes for DUX4 antibodies
Middle Region
Reactivity
All reactivities for DUX4 antibodies
Human
Host
All hosts for DUX4 antibodies
Rabbit
Clonality
All clonalities for DUX4 antibodies
Polyclonal
Conjugate
All conjugates for DUX4 antibodies
This DUX4 antibody is un-conjugated
Application
All applications for DUX4 antibodies
Western Blotting (WB)
Sequence
ESRPWPGRRG PPEGRRKRTA VTGSQTALLL RAFEKDRFPG IAAREELARE
Predicted Reactivity
Human: 85%
Characteristics
This is a rabbit polyclonal antibody against DUX4. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human DUX4
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Discover our top product DUX4 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for DUX4
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Target
DUX4
(Double Homeobox 4 (DUX4))
Alternative Name
DUX4 (DUX4 Products )
Synonyms
DUX4 antibody, DUX4L antibody, double homeobox, 4 antibody, double homeobox 4 antibody, DUX4 antibody
Background
This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length, a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes, the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1, GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants. Alias Symbols: DUX4L Protein Size: 424
Gene ID
100288687
NCBI Accession
NM_001293798 , NP_001280727
UniProt
Q9UBX2
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