SMARCAL1 antibody (N-Term)

Catalog No. ABIN5516775

Product Details anti-SMARCAL1 Antibody

Target: SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A-Like 1 (SMARCAL1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Cow, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMARCAL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LTEEQRKKIE ENRQKALARR AEKLLAEQHQ RTSSGTSIAG NPFQAKQGPS

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against SMARCAL1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SMARCAL1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SMARCAL1

Target: SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A-Like 1 (SMARCAL1))

Alternative Name: SMARCAL1 (SMARCAL1 Products)

Synonyms: SMARCAL1 antibody, im:7145331 antibody, si:ch211-239d11.1 antibody, harp antibody, hharp antibody, 6030401P21Rik antibody, AI851716 antibody, Mharp antibody, HARP antibody, HHARP antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 antibody, SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 antibody, Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 L homeolog antibody, SMARCAL1 antibody, smarcal1 antibody, Smarcal1 antibody, smarcal1.L antibody

Background: The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.

Alias Symbols: SMARCAL1, HARP,

Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, SULT1A1, Cebpb,

Protein Size: 954

Gene ID: 50485

NCBI Accession: XP_005246689

UniProt: Q9NZC9

Pathways: Embryonic Body Morphogenesis