HBG2 antibody (C-Term)

Catalog No. ABIN5516891

Product Details anti-HBG2 Antibody

Target: HBG2 (Hemoglobin, gamma G (HBG2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBG2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KLHVDPENFK LLGNVLVTVL AIHFGKEFTP EVQASWQKMV TGVASALSSR

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HBG2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HBG2

Target: HBG2 (Hemoglobin, gamma G (HBG2))

Alternative Name: HBG2 (HBG2 Products)

Synonyms: TNCY antibody, hbb2 antibody, MGC88976 antibody, HBG antibody, hemoglobin subunit gamma 2 antibody, hemoglobin subunit gamma 2 L homeolog antibody, hemoglobin, gamma G antibody, hemoglobin subunit gamma 2 S homeolog antibody, HBG2 antibody, hbg2 antibody, hbg2.L antibody, hbg2.S antibody

Background: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Alias Symbols: TNCY, HBG-T1,

Protein Size: 167

Gene ID: 3048

NCBI Accession: NM_000184, NP_000175

UniProt: P69892