GLDC antibody (C-Term)

Catalog No. ABIN5516905

Product Details anti-GLDC Antibody

Target: GLDC (Glycine Dehydrogenase (GLDC))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLDC antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ANIEAVDVAK RLQDYGFHAP TMSWPVAGTL MVEPTESEDK AELDRFCDAM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GCSP. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GCSP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GLDC

Target: GLDC (Glycine Dehydrogenase (GLDC))

Alternative Name: GCSP (GLDC Products)

Synonyms: PSPTO1276 antibody, Tb07.43M14.350 antibody, DDBDRAFT_0219205 antibody, DDBDRAFT_0231130 antibody, DDB_0219205 antibody, DDB_0231130 antibody, D030049L12Rik antibody, D19Wsu57e antibody, GCE antibody, GCSP antibody, HYGN1 antibody, fb23b05 antibody, wu:fb23b05 antibody, zgc:66198 antibody, gldc antibody, glycine dehydrogenase (decarboxylating) GcvP antibody, glycine dehydrogenase antibody, glycine cleavage system P-protein antibody, glycine decarboxylase antibody, glycine dehydrogenase (decarboxylating) antibody, glycine decarboxylase S homeolog antibody, gcvP antibody, Tb927.7.1910 antibody, Gldc antibody, GLDC antibody, gldc antibody, gldc.S antibody

Background: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).

Alias Symbols: GLDC, GCSP,

Protein Interaction Partner: SUZ12, UBC, CUL2, TNFAIP3, TLR10, GLDC,

Protein Size: 1020

Gene ID: 2731

NCBI Accession: NP_000161

UniProt: P23378