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KDM4B antibody (N-Term)
KDM4B
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-KDM4B Antibody
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Target
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KDM4B
(Lysine (K)-Specific Demethylase 4B (KDM4B))
Binding Specificity
All epitopes for KDM4B antibodies
N-Term
Reactivity
All reactivities for KDM4B antibodies
Human
Host
All hosts for KDM4B antibodies
Rabbit
Clonality
All clonalities for KDM4B antibodies
Polyclonal
Conjugate
All conjugates for KDM4B antibodies
This KDM4B antibody is un-conjugated
Application
All applications for KDM4B antibodies
Western Blotting (WB)
Sequence
IPPKEWKPRQ TYDDIDDVVI PAPIQQVVTG QSGLFTQYNI QKKAMTVGEY
Characteristics
This is a rabbit polyclonal antibody against KDM4B. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human KDM4B
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for KDM4B
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Target
KDM4B
(Lysine (K)-Specific Demethylase 4B (KDM4B))
Alternative Name
KDM4B (KDM4B Products )
Synonyms
KDM4B antibody, JMJD2B antibody, jmjd2b antibody, si:ch211-124a3.4 antibody, TDRD14B antibody, 4732474L06Rik antibody, Jmjd2b antibody, mKIAA0876 antibody, lysine demethylase 4B antibody, lysine (K)-specific demethylase 4B antibody, KDM4B antibody, kdm4b antibody, Kdm4b antibody
Background
KDM4B is a histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. It does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. Alias Symbols: KDM4B, JHDM3B, JMJD2B, KIAA0876, Protein Interaction Partner: UBC, H3F3C, HSP90B1, HSP90AA2P, SMU1, KMT2C, WDR5, ASH2L, KMT2D, RBBP5, HSPA4, HNRNPU, ESR1, MED10, Protein Size: 1096
Gene ID
23030
NCBI Accession
NP_055830
UniProt
O94953
Pathways
Warburg Effect
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