PRAM1 antibody (Middle Region)

Catalog No. ABIN5517264

Product Details anti-PRAM1 Antibody

Target: PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRAM1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HFQDRQPEDI PQVPDEIYEL YDDVEPRDDS SPSPKGRDEA PSVQQAARRP

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PRAM1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRAM1

Target: PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))

Alternative Name: PRAM1 (PRAM1 Products)

Synonyms: PRAM1 antibody, AY665714 antibody, PML-RAR antibody, PRAM-1 antibody, RGD1564330 antibody, PML-RARA regulated adaptor molecule 1 antibody, PML-RAR alpha-regulated adaptor molecule 1 antibody, PRAM1 antibody, Pram1 antibody

Background: The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha).

Alias Symbols: PRAM-1, PML-RAR

Protein Size: 718

Gene ID: 84106

NCBI Accession: NM_032152, NP_115528

UniProt: Q96QH2

Pathways: Regulation of Leukocyte Mediated Immunity