WIPI1 antibody (Middle Region)

Catalog No. ABIN5517383

Product Details anti-WIPI1 Antibody

Target: WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WIPI1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LGSGTTEENK ENDLRPSLPQ SYAATVARPS ASSASTVPGY SEDGGALRGE

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human WIPI1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for WIPI1

Target: WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))

Alternative Name: WIPI1 (WIPI1 Products)

Synonyms: ATG18 antibody, ATG18A antibody, WIPI49 antibody, 4930533H01Rik antibody, AW411817 antibody, D11Ertd498e antibody, RGD1307754 antibody, zgc:64205 antibody, WIPI1 antibody, atg18 antibody, wipi49 antibody, MGC145296 antibody, rgs9 antibody, wipi1 antibody, zgc:152760 antibody, WD repeat domain, phosphoinositide interacting 1 antibody, WD repeat domain, phosphoinositide interacting 1 S homeolog antibody, regulator of G protein signaling 9a antibody, WIPI1 antibody, Wipi1 antibody, wipi1 antibody, wipi1.S antibody, rgs9a antibody

Background: This gene encodes a WD40 repeat protein. Members of the WD40 repeat family are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids. Alternative splicing results in multiple transcript variants.

Alias Symbols: ATG18, ATG18A, WIPI49

Protein Size: 446

Gene ID: 55062

NCBI Accession: NM_017983, NP_060453

UniProt: Q5MNZ9

Pathways: Nuclear Hormone Receptor Binding, ER-Nucleus Signaling