UBXN8 antibody (Middle Region)

Catalog No. ABIN5517391

The Rabbit Polyclonal anti-UBXN8 antibody is suitable to detect UBXN8 in samples from Human. It has been validated for WB.

Quick Overview for UBXN8 antibody (Middle Region) (ABIN5517391)

Target: UBXN8 (UBX Domain Protein 8 (UBXN8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBXN8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UBXN8 Antibody

Binding Specificity: Middle Region

Purpose: UBXN8 Antibody - middle region

Sequence: RKLEERFYQM TGEAWKLSSG HKLGGDEGTS QTSFETSNRE AAKSQNLPKP

Characteristics: This is a rabbit polyclonal antibody against UBXN8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human UBXN8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP73656-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for UBXN8

Target: UBXN8 (UBX Domain Protein 8 (UBXN8))

Alternative Name: UBXN8

Background:

Background Information: p97 or VCP (valosin-containing protein) is a versatile ATPase complex, and many cofactors are required for the p97 functional diversity. This gene encodes one of the p97 cofactors. This cofactor is a transmembrane protein and localized in the endoplasmic reticulum (ER) membrane. It tethers p97 to the ER membrane via its UBX domain. The association of this cofactor with p97 facilitates efficient ER-associated degradation of misfolded proteins. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative Symbols: REP8, UBXD6, D8S2298E

Molecular Weight: 29kDa

Gene ID: 7993

NCBI Accession: NP_005662

UniProt: O00124

Pathways: SARS-CoV-2 Protein Interactome