RGC32 antibody (Middle Region)

Catalog No. ABIN5517500

Product Details anti-RGC32 Antibody

Target: RGC32 (C13orf15) (Chromosome 13 Open Reading Frame 15 (C13orf15))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGC32 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HERHFHYEEH LERMKRRSSA SVSDSSGFSD SESADSLYRN SFSFSDEKLN

Characteristics: This is a rabbit polyclonal antibody against RGCC. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human RGCC

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGC32

Target: RGC32 (C13orf15) (Chromosome 13 Open Reading Frame 15 (C13orf15))

Alternative Name: RGCC (C13orf15 Products)

Synonyms: C13orf15 antibody, RGC-32 antibody, RGC32 antibody, bA157L14.2 antibody, 1190002H23Rik antibody, Rgc-32 antibody, Rgc32 antibody, C12H13orf15 antibody, sb:cb658 antibody, wu:fa94a05 antibody, zgc:91870 antibody, regulator of cell cycle antibody, RGCC antibody, Rgcc antibody, rgcc antibody

Background: This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression.

Alias Symbols: RGCC, C13orf15, RGC32,

Protein Interaction Partner: CDK1, AKT1, SMAD3, SMAD2,

Protein Size: 137

Gene ID: 28984

NCBI Accession: NP_054778

UniProt: Q9H4X1