Tropomyosin antibody (N-Term)
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- Target See all Tropomyosin (TPM1) Antibodies
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Mouse, Zebrafish (Danio rerio), Rabbit, Cow, Horse, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Tropomyosin antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- DAEADVASLN RRIQLVEEEL DRAQERLATA LQKLEEAEKA ADESERGMKV
- Predicted Reactivity
- Cow: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against TPM1. It was validated on Western Blot.
- Purification
- Affinity purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human TPM1
- Top Product
- Discover our top product TPM1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
- Alternative Name
- TPM1 (TPM1 Products)
- Synonyms
- alpha-fTM antibody, Tm7 antibody, tpm1 antibody, MGC84844 antibody, AA986836 antibody, AI854628 antibody, TM2 antibody, Tm3 antibody, Tmpa antibody, Tpm-1 antibody, alpha-TM antibody, Alpha-tm antibody, Tma2 antibody, Tmsa antibody, TPM1 antibody, fb37a09 antibody, tm antibody, wu:fb37a09 antibody, CH1 antibody, alpha-tm antibody, alpha-tropomyosin antibody, C15orf13 antibody, CMD1Y antibody, CMH3 antibody, HTM-alpha antibody, TMSA antibody, TPMA antibody, Tm1 antibody, zgc:171719 antibody, zgc:55951 antibody, zgc:77009 antibody, tropomyosin 1 (alpha) antibody, tropomyosin antibody, tropomyosin 1 antibody, tropomyosin 1, alpha antibody, alpha-tropomyosin antibody, tropomyosin 1 L homeolog antibody, TPM1 antibody, tm7 antibody, Tpm1 antibody, tpma antibody, tpm1.L antibody, Smp_044010.2 antibody, LOC732984 antibody, tpm1 antibody
- Background
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This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
Alias Symbols: TPM1, C15orf13, TMSA,
Protein Interaction Partner: GOLGA2, CAGE1, C1orf216, SYCE1, KXD1, TFPT, MAD1L1, TPM4, TP53, TNNT1, UBC, MDM2, ETFA, FOXK1, KIAA1598, PPP6R3, APPL2, CDC37, MGEA5, STUB1, ABI2, DNAJC7, HSP90B1, PARK2, LRCH3, PAN2, TGFBR1, SPTBN1, ATF2, MDC1, BRCA1, PPP4R2, SRXN1, NUDCD2, RBM15, THOC2,
Protein Size: 284 - Gene ID
- 7168
- NCBI Accession
- XP_006720731
- UniProt
- P09493
- Pathways
- Regulation of Actin Filament Polymerization
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