CACTIN antibody (C-Term)

Catalog No. ABIN5517885

This Rabbit Polyclonal antibody specifically detects CACTIN in WB. It exhibits reactivity toward Human.

Quick Overview for CACTIN antibody (C-Term) (ABIN5517885)

Target: CACTIN (Cactin, Spliceosome C Complex Subunit (CACTIN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACTIN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CACTIN Antibody

Binding Specificity: C-Term

Sequence: ADKYRPRKPR FFNRVHTGFE WNKYNQTHYD FDNPPPKIVQ GYKFNIFYPD

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human C19ORF29

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CACTIN

Target: CACTIN (Cactin, Spliceosome C Complex Subunit (CACTIN))

Alternative Name: C19ORF29

Background: Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. May play a role during early embryonic development. Probably involved in pre-mRNA splicing.

Alias Symbols: fSAPc, C19orf29, NY-REN-24

Protein Size: 758

Gene ID: 58509

NCBI Accession: NM_001080543, NP_001074012

UniProt: Q8WUQ7

Pathways: Cellular Response to Molecule of Bacterial Origin