PON1 antibody (AA 30-274)

Catalog No. ABIN5519053

Product Details anti-PON1 Antibody

Target: PON1 (Paraoxonase 1 (PON1))

Binding Specificity: AA 30-274

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for PON1 detection. Tested with WB, IHC-P, ELISA(Cap) in Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for PON1 detection. Tested with WB, IHC-P, ELISA(Cap) in Mouse,Rat.
Gene Name: paraoxonase 1
Protein Name: Serum paraoxonase/arylesterase 1

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse PON1 recombinant protein (Position: A30-D274).

Isotype: IgG

Application Details

Application Notes: Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for PON1

Target: PON1 (Paraoxonase 1 (PON1))

Alternative Name: Pon1 (PON1 Products)

Synonyms: esa antibody, pon antibody, pon2 antibody, MGC53915 antibody, MGC89222 antibody, PON1 antibody, ESA antibody, MVCD5 antibody, PON antibody, Pon antibody, paraoxonase 2 antibody, paraoxonase 1 antibody, pon2 antibody, PON1 antibody, Pon1 antibody

Background: Serum paraoxonase/arylesterase 1 (PON1), also known as aromatic esterase 1, is an enzyme that in humans is encoded by the PON1 gene. It is mapped to 7q21.3. This gene has esterase and more specifically paraoxonase activity. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL). The PON1 gene is activated by PPAR-γ, which increases synthesis and release of paraoxonase 1 enzyme from the liver, reducing atherosclerosis.

Synonyms: Serum paraoxonase/arylesterase 1, PON 1

Gene ID: 18979

UniProt: P52430