GRAF antibody (AA 237-267)

Catalog No. ABIN5530294

Product Details anti-GRAF Antibody

Target: GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))

Binding Specificity: AA 237-267

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRAF antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This GRAF (OPHN1L) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-267 amino acids from the Central region of human GRAF (OPHN1L).

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for GRAF

Target: GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))

Alternative Name: GRAF (ARHGAP26 Products)

Synonyms: ARHGAP26 antibody, GRAF antibody, GRAF1 antibody, OPHN1L antibody, OPHN1L1 antibody, 1810044B20Rik antibody, 2610010G17Rik antibody, 4933432P15Rik antibody, AI853435 antibody, mKIAA0621 antibody, Rho GTPase activating protein 26 antibody, ARHGAP26 antibody, Arhgap26 antibody

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

Molecular Weight: 92 kDa

Gene ID: 23092

UniProt: Q9UNA1