Calpain 3 antibody (C-Term)

Catalog No. ABIN5530737

Product Details anti-Calpain 3 Antibody

Target: Calpain 3 (CAPN3)

Binding Specificity: AA 603-632, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calpain 3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This CAPN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 603-632 amino acids from the C-terminal region of human CAPN3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Calpain 3

Target: Calpain 3 (CAPN3)

Alternative Name: CAPN3 (CAPN3 Products)

Synonyms: capn3 antibody, MGC80925 antibody, zgc:92687 antibody, CAPN3 antibody, AI323605 antibody, Capa-3 antibody, Capa3 antibody, Lp82 antibody, p94 antibody, Lp84 antibody, Lp85 antibody, CANP3 antibody, CANPL3 antibody, LGMD2 antibody, LGMD2A antibody, nCL-1 antibody, SKM-CALP antibody, SKM-CALPOV antibody, nCL1 antibody, calpain 1, (mu/I) large subunit L homeolog antibody, calpain 3a, (p94) antibody, calpain 3 antibody, capn1.L antibody, capn3a antibody, CAPN3 antibody, Capn3 antibody

Background: Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A.

Molecular Weight: 94 kDa

Gene ID: 825

UniProt: P20807

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development