DUSP10 antibody (AA 204-232)
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- Target See all DUSP10 Antibodies
- DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
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Binding Specificity
- AA 204-232
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DUSP10 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This DUSP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-232 amino acids from the Central region of human DUSP10.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product DUSP10 Primary Antibody
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- Application Notes
- For WB starting dilution is: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
- Alternative Name
- DUSP10 (DUSP10 Products)
- Synonyms
- DUSP10 antibody, MKP-5 antibody, MKP5 antibody, 2610306G15Rik antibody, AI158871 antibody, Mkp-5 antibody, Mkp5 antibody, dual specificity phosphatase 10 antibody, DUSP10 antibody, Dusp10 antibody
- Background
- Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique, it is evenly distributed in both the cytoplasm and the nucleus. This gene is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene.
- Molecular Weight
- 53 kDa
- Gene ID
- 11221
- UniProt
- Q9Y6W6
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