Junctophilin 2 antibody (C-Term)

Catalog No. ABIN5531487

Product Details anti-Junctophilin 2 Antibody

Target: Junctophilin 2 (JPH2)

Binding Specificity: AA 614-643, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Junctophilin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This JPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 614-643 amino acids from the C-terminal region of human JPH2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Junctophilin 2

Target: Junctophilin 2 (JPH2)

Alternative Name: JPH2 (JPH2 Products)

Synonyms: CMH17 antibody, JP-2 antibody, JP2 antibody, jp antibody, 1110002E14Rik antibody, Jp2 antibody, junctophilin 2 antibody, junctophilin-2 antibody, JPH2 antibody, LOC100461095 antibody, LOC610874 antibody, Jph2 antibody

Background: Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described.

Molecular Weight: 74 kDa

Gene ID: 57158

UniProt: Q9BR39