MCPH1 antibody (N-Term)

Catalog No. ABIN5531653

Product Details anti-MCPH1 Antibody

Target: MCPH1 (Microcephalin 1 (MCPH1))

Binding Specificity: AA 104-133, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCPH1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MCPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human MCPH1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for MCPH1

Target: MCPH1 (Microcephalin 1 (MCPH1))

Alternative Name: MCPH1 (MCPH1 Products)

Synonyms: RGD1560642 antibody, MGC83773 antibody, MCPH1 antibody, mct antibody, brit1 antibody, MGC148665 antibody, BRIT1 antibody, MCT antibody, 5430437K10Rik antibody, D030046N04Rik antibody, microcephalin 1 antibody, microcephalin 1 S homeolog antibody, microcephaly, primary autosomal recessive 1 antibody, Mcph1 antibody, mcph1.S antibody, MCPH1 antibody, mcph1 antibody

Background: This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.

Molecular Weight: 93 kDa

Gene ID: 79648

UniProt: Q8NEM0

Pathways: Stem Cell Maintenance