TP53RK antibody (AA 220-249)

Catalog No. ABIN5532257

Product Details anti-TP53RK Antibody

Target: TP53RK (TP53 Regulating Kinase (TP53RK))

Binding Specificity: AA 220-249

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TP53RK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This PRPK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-249 amino acids from the Central region of human PRPK.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TP53RK

Target: TP53RK (TP53 Regulating Kinase (TP53RK))

Alternative Name: PRPK (TP53RK Products)

Synonyms: BUD32 antibody, C20orf64 antibody, Nori-2 antibody, Nori-2p antibody, PRPK antibody, dJ101A2 antibody, 2810408M09Rik antibody, 4933401B08Rik antibody, 5630401H01Rik antibody, Tp53rk antibody, Trp53tk antibody, mNori-2p antibody, Trp53rk antibody, TP53RK antibody, fd05d02 antibody, wu:fd05d02 antibody, zgc:110000 antibody, MGC115438 antibody, T1N24.12 antibody, T1N24_12 antibody, TP53 regulating kinase antibody, transformation related protein 53 regulating kinase B antibody, TP53 regulating kinase L homeolog antibody, Protein kinase superfamily protein antibody, TP53RK antibody, Trp53rkb antibody, Tp53rk antibody, tp53rk antibody, tp53rk.L antibody, AT5G26110 antibody, GL50803_16796 antibody

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

Molecular Weight: 28 kDa

Gene ID: 112858

UniProt: Q96S44