UBP1 antibody (AA 266-295)

Catalog No. ABIN5532759

Product Details anti-UBP1 Antibody

Target: UBP1 (Upstream Binding Protein 1 (LBP-1a) (UBP1))

Binding Specificity: AA 266-295

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-295 amino acids from the Central region of human UBP1.

Isotype: Ig Fraction

Application Details

Application Notes: For IF starting dilution is: 1:10~50

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for UBP1

Target: UBP1 (Upstream Binding Protein 1 (LBP-1a) (UBP1))

Alternative Name: UBP1 (UBP1 Products)

Synonyms: UBP1 antibody, cp2 antibody, cp-2 antibody, lbp1 antibody, lbp-1 antibody, ubp-1 antibody, Cp2b antibody, LBP-1a antibody, LBP-1b antibody, NF2d9 antibody, LBP-1B antibody, LBP1A antibody, LBP1B antibody, RGD1564700 antibody, upstream binding protein 1 antibody, upstream binding protein 1 L homeolog antibody, upstream binding protein 1 (LBP-1a) antibody, UBP1 antibody, ubp1.L antibody, ubp1 antibody, Ubp1 antibody

Background: UBP1 functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.

Molecular Weight: 60 kDa

Gene ID: 7342

UniProt: Q9NZI7