This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ARAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-93 amino acids from the N-terminal region of human ARAP2.
ARAP2
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
Biotin
Application Notes
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
ARAP2
(ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 2 (ARAP2))
CENTD1 antibody, PARX antibody, Centd1 antibody, Gm148 antibody, mKIAA0580 antibody, ARAP2 antibody, ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 antibody, arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 antibody, ARAP2 antibody, Arap2 antibody, LOC100567363 antibody
Background
The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics.