ATP6V1F antibody (C-Term)

Catalog No. ABIN5532806

Product Details anti-ATP6V1F Antibody

Target: ATP6V1F (ATPase, H+ Transporting, Lysosomal 14kDa, V1 Subunit F (ATP6V1F))

Binding Specificity: AA 82-111, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V1F antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATP6V1F antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-111 amino acids from the C-terminal region of human ATP6V1F.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ATP6V1F

Target: ATP6V1F (ATPase, H+ Transporting, Lysosomal 14kDa, V1 Subunit F (ATP6V1F))

Alternative Name: ATP6V1F (ATP6V1F Products)

Synonyms: Atp6s14 antibody, Vma7 antibody, atp6s14 antibody, atp6v1f antibody, vatf antibody, ATP6S14 antibody, VATF antibody, 1110004G16Rik antibody, ATPase H+ transporting V1 subunit F antibody, ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F S homeolog antibody, ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F L homeolog antibody, ATPase, H+ transporting, lysosomal V1 subunit F antibody, Atp6v1f antibody, atp6v1f.S antibody, ATP6V1F antibody, atp6v1f.L antibody

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is the V1 domain F subunit protein.

Molecular Weight: 13 kDa

Gene ID: 9296

UniProt: Q16864

Pathways: Transition Metal Ion Homeostasis, Proton Transport