ADCY8 antibody (AA 946-972)

Catalog No. ABIN5532812

Product Details anti-ADCY8 Antibody

Target: ADCY8 (Adenylate Cyclase 8 (Brain) (ADCY8))

Binding Specificity: AA 946-972

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ADCY8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 946-972 amino acids from the Central region of human ADCY8.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.48 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ADCY8

Target: ADCY8 (Adenylate Cyclase 8 (Brain) (ADCY8))

Alternative Name: ADCY8 (ADCY8 Products)

Synonyms: MGC121231 antibody, si:ch211-220f13.4 antibody, AC8 antibody, AW060868 antibody, ADCY3 antibody, HBAC1 antibody, Ac8 antibody, adenylate cyclase 8 (brain) S homeolog antibody, adenylate cyclase 8 antibody, adenylate cyclase 8 (brain) antibody, adenylate cyclase type 8 antibody, adenylate cyclase 3 antibody, adcy8.S antibody, ADCY8 antibody, adcy8 antibody, LOC100461383 antibody, Adcy8 antibody, ADCY3 antibody

Background: ADCY8 is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase provided by RefSeq].

Molecular Weight: 140 kDa

Gene ID: 114

UniProt: P40145

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma